General Information of HGF (ID: HGF2338)
HGF Name HES1
HGF Synonym(s) HHL, HRY, HES-1, bHLHb39, hes family bHLH transcription factor 1
Source Homo sapiens
HGF Classification Copy Number Variation: Gene Deletion (CNV-GDe)
Gene Location chr3
Gene Start Site 194136148 Gene End Site 194138732
Strand Forward (+)
External Links
Ensembl ID
ENSG00000114315
Microbe Species (MIC) Regulated by This HGF
         Akkermansia muciniphila (verrucomicrobia) MIC00056
             Description The deletion of HES1 was significantly associated with the increased abundance of Akkermansia muciniphila (p-value<0.0001). [1]
         Bacteroidetes (CFB bacteria) MIC00141
             Description The deletion of HES1 was significantly associated with the decreased abundance of Bacteroidetes (p-value<0.005). [1]
         Escherichia coli (enterobacteria) MIC00516
             Description The deletion of HES1 was significantly associated with an increase of Escherichia coli (p-value<0.05). [1]
References
1 Epithelial Hes1 maintains gut homeostasis by preventing microbial dysbiosis.Mucosal Immunol. 2018 May;11(3):716-726. doi: 10.1038/mi.2017.111. Epub 2018 Jan 3.

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