| General Information of HGF (ID: HGF2340) |
| HGF Name |
NINJ1
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| HGF Synonym(s) |
NIN1, NINJURIN, ninjurin 1
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| Source |
Homo sapiens
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| HGF Classification |
Copy Number Variation: Gene Deletion (CNV-GDe)
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| Gene Location |
chr9
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| Gene Start Site |
93121496
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Gene End Site |
93134251
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| Strand |
Reverse (-)
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| External Links |
| Ensembl ID |
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| Microbe Species (MIC) Regulated by This HGF |
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Lachnospiraceae (firmicutes)
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MIC00695
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| Description |
The deletion of NINJ1 was significantly associated with a decreased abundance of the Lachnospiraceae (p-value<0.05). |
[1] |
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Prevotellaceae (CFB bacteria)
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MIC01028
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| Description |
The deletion of NINJ1 increased the relative abundance of Prevotellaceae. |
[1] |
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| References |
| 1 |
Ninjurin1 deficiency aggravates colitis development by promoting M1 macrophage polarization and inducing microbial imbalance.FASEB J. 2020 Jun;34(6):8702-8720. doi: 10.1096/fj.201902753R. Epub 2020 May 8.
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