General Information of HIF (ID: HIFC0007)
HIF Name	Eosinophils
HIF Synonym(s)	Eosinophils
HIF Classification	Granulocytes (Gra)
Description	These increases were ablated in MyD88 / mice, and NF-B p65 was phosphorylated in response to T. muris excretory/secretory products in the epithelial cell line CMT-93, suggesting involvement of the MyD88-NF-B signaling pathway in IEC cytokine expression.				[1]

Microbe Species (MIC) Regulated by This HIF
Spirochaetes (bacteria)			MIC01204
Description	Leucine-rich repeat (LrrA) of oral spirochaetes involved the adherence and penetration of epithelial cells.				[2]

References
1	The innate immune responses of colonic epithelial cells to Trichuris muris are similar in mouse strains that develop a type 1 or type 2 adaptive immune response. Infect Immun. 2006 Nov;74(11):6280-6. doi: 10.1128/IAI.01609-05.
2	New insights into the emerging role of oral spirochaetes in periodontal disease. Clin Microbiol Infect. 2011 Apr;17(4):502-12. doi: 10.1111/j.1469-0691.2011.03460.x.

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