Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFC0079)
HIF Name	Normal T-cell expressed and secreted
HIF Synonym(s)	normal T-cell expressed and secreted (RANTES), Normal T-cell expressed and secreted
HIF Classification	T cells (TCs)
Description	CC chemokine ligand-5, or regulated on activation, normal T-cell expressed, and secreted (RANTES), is a CC chemokine that is expressed by cell types such as T-cells, fibroblasts, and mesangial cells and also stored in the alpha granules of platelets.	[1]

Microbe Species (MIC) Regulated by This HIF
Chlamydia pneumoniae (chlamydias)		MIC00350
Description	Chlamydophila pneumoniae could increase normal T-cell expressed and secreted (RANTES).		[2]

References
1	Relationship between circulating levels of RANTES (regulated on activation, normal T-cell expressed, and secreted) and carotid plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study. Eur Heart J. 2011 Feb;32(4):459-68. doi: 10.1093/eurheartj/ehq367. Epub 2010 Oct 12.
2	Chlamydia pneumoniae Infection and Inflammatory Diseases. For Immunopathol Dis Therap. 2016;7(3-4):237-254. doi: 10.1615/ForumImmunDisTher.2017020161.

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