General Information of HIF (ID: HIFC0084)
HIF Name
FOXP3+CD127lo CD4+ T cells
HIF Synonym(s)
FOXP3+CD127lo CD4+, FOXP3+CD127lo CD4+ T cells
HIF Classification
T cells (TCs)
Description FOXP3 expressing CD127lo CD4+ T cells inversely correlate with CD38+ CD8+ T cell activation levels in primary HIV-1 infection. [1]
Microbe Species (MIC) Regulated by This HIF
         Human immunodeficiency virus 1 (viruses) MIC02009
             Description FOXP3+CD127lo CD4+ T cells may reduce the levels of T cell activation following primary HIV-infection. [2]
References
1 Regulatory T cells in retroviral infections.PLoS Pathog. 2018 Feb 15;14(2):e1006776. doi: 10.1371/journal.ppat.1006776. eCollection 2018 Feb.
2 FOXP3 expressing CD127lo CD4+ T cells inversely correlate with CD38+ CD8+ T cell activation levels in primary HIV-1 infection.J Leukoc Biol. 2008 Feb;83(2):254-62. doi: 10.1189/jlb.0507281. Epub 2007 Nov 2.

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