General Information of HIF (ID: HIFC0089)
HIF Name
Vg9Vd2 T cells
HIF Synonym(s)
Vg9Vd2 T-cells, Vg9Vd2 T cells
HIF Classification
T cells (TCs)
Description Human Vgamma9Vdelta2 T cells, a major innate-like peripheral T cell subset, are thought to play in vivo akey role in innate and adaptive immune responses to infection agents and tumors. [1]
Microbe Species (MIC) Regulated by This HIF
         Brucella suis (alpha-proteobacteria) MIC00275
             Description Brucella suis stimulated human Vg9Vd2 T-cells to secrete TNF alpha, IFN-gamma and other not yet identified cytokines. [2]
References
1 Metabolic approaches to rescue antitumor V9V2 T-cell functions in myeloma.Front Biosci (Landmark Ed). 2020 Jan 1;25:69-105.
2 The innate immune response against Brucella in humans. Vet Microbiol. 2002 Dec 20;90(1-4):383-94. doi: 10.1016/s0378-1135(02)00223-7.

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