General Information of HIF (ID: HIFM0034)
HIF Name	C-C motif chemokine 7
HIF Synonym(s)	mcp3, protein mcp3, mug7
HIF Classification	Cytokine (Cyt)
Molecular Function	Cytokine; Heparin-binding
Description	Monocyte chemotactic protein 3 (MCP-3) is a secreted chemokine which attracts macrophages during inflammation and metastasis.				[1]
Pfam	Small cytokines (intecrine/chemokine), interleukin-8 like (PF00048 )
Pathway	Chemokine signaling pathway (hsa04062 )
	Cytokine-cytokine receptor interaction (hsa04060 )
	IL-17 signaling pathway (hsa04657 )
	Viral protein interaction with cytokine and cytokine receptor (hsa04061 )
Sequence	Click here to download the HIF sequence in FASTA format
External Links
	Uniprot ID	CCL7_HUMAN

Microbe Species (MIC) Regulated by This HIF
Eggerthella lenta (actinobacteria)			MIC00520
Description	At the genus level, Eggerthella is associated with the MCP-3 expression.				[2]

References
1	Tumor-associated macrophage/microglia infiltration in human gliomas is correlated with MCP-3, but not MCP-1.Int J Oncol. 2009 Jun;34(6):1621-7. doi: 10.3892/ijo_00000292.
2	Autoimmunity-Associated Gut Commensals Modulate Gut Permeability and Immunity in Humanized Mice. Mil Med. 2019 Mar 1;184(Suppl 1):529-536. doi: 10.1093/milmed/usy309.

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