General Information of HIF (ID: HIFM0038)
HIF Name	T-cell surface glycoprotein CD1a
HIF Synonym(s)	CD1a, CD1A
HIF Classification	Checkpoint molecule (CM)
Description	CD1molecules(CD1a in human) enables presentation of foreign microbial lipids for specific T cell recognition.				[1]
Pfam	Immunoglobulin C1-set domain (PF07654 )
	MHC-I family domain (PF16497 )
Pathway	Amoebiasis (hsa05146 )
	Hematopoietic cell lineage (hsa04640 )
	Tight junction (hsa04530 )
Sequence	Click here to download the HIF sequence in FASTA format
External Links
	Uniprot ID	CD1A_HUMAN

Microbe Species (MIC) Regulated by This HIF
Cutibacterium acnes (actinobacteria)			MIC01031
Description	The increased Propionibacterium acnes abundance was associated with the expression of langerhans cell marker CD1a/CD207.				[2]

References
1	CD1-dependent dendritic cell instruction.Nat Immunol. 2002 Dec;3(12):1163-8. doi: 10.1038/ni851. Epub 2002 Nov 4.
2	Microbiome in the hair follicle of androgenetic alopecia patients.PLoS One. 2019 May 3;14(5):e0216330. doi: 10.1371/journal.pone.0216330. eCollection 2019.

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