Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFM0044)
HIF Name
Tumor necrosis factor receptor superfamily member 7
HIF Synonym(s)
CD27L receptor, T-cell activation antigen CD27, T14, CD27
HIF Classification
Checkpoint molecule (CM)
Molecular Function
Receptor
Description CD27 is reported to be crucial immune modulator [1]
Pfam TNFR/NGFR cysteine-rich region (PF00020 )
Pathway Cytokine-cytokine receptor interaction (hsa04060 )
Sequence Click here to download the HIF sequence in FASTA format
External Links
Uniprot ID
CD27_HUMAN
Microbe Species (MIC) Regulated by This HIF
         Bifidobacterium sp. (actinobacteria) MIC00224
             Description The abundance of Bifidobacteria was associated with higher numbers of CD20(+) B cells that expressed the memory marker CD27 at 4 and 18 mo of age. [2]
         Escherichia coli (enterobacteria) MIC00516
             Description The abundance of Escherichia coli was associated with higher numbers of CD20(+) B cells that expressed the memory marker CD27 at 4 and 18 month of age. [2]
References
1 Exploration of a novel prognostic risk signatures and immune checkpoint molecules in endometrial carcinoma microenvironment.Genomics. 2020 Sep;112(5):3117-3134. doi: 10.1016/j.ygeno.2020.05.022. Epub 2020 May 29.
2 Infant B cell memory differentiation and early gut bacterial colonization.J Immunol. 2012 May 1;188(9):4315-22. doi: 10.4049/jimmunol.1103223. Epub 2012 Apr 4.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.