Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFM0075)
HIF Name
C-X-C motif chemokine 11
HIF Synonym(s)
C-X-C motif chemokine ligand 11, H174, I-TAC, IP-9, IP9, SCYB11, SCYB9B, b-R1
HIF Classification
Cytokine (Cyt)
Molecular Function
Cytokine
Description CXCL11 (C-X-C Motif Chemokine Ligand 11) is a Protein Coding gene. Diseases associated with CXCL11 include Nasal Cavity Cancer and Nasal Cavity Adenocarcinoma. Among its related pathways are Signaling by GPCR and CCR5 Pathway in Macrophages. [1]
Pfam Small cytokines (intecrine/chemokine), interleukin-8 like (PF00048 )
Pathway Chemokine signaling pathway (hsa04062 )
Cytokine-cytokine receptor interaction (hsa04060 )
Toll-like receptor signaling pathway (hsa04620 )
Viral protein interaction with cytokine and cytokine receptor (hsa04061 )
Sequence Click here to download the HIF sequence in FASTA format
External Links
Uniprot ID
CXL11_HUMAN
Microbe Species (MIC) Regulated by This HIF
         Bacteroidetes (CFB bacteria) MIC00141
             Description The presence of the genus Bacteroides was associated with high levels of the Th1-associated chemokines CXCL11 during infancy. [2]
         Phascolarctobacterium faecium (firmicutes) MIC00983
             Description At the genus level, Phascolarctobacterium is associated with the CXCL11 expression. [3]
References
1 Serum CXCL11 correlates with pulmonary outcomes and disease burden in sarcoidosis.Respir Med. 2019 Jun;152:89-96. doi: 10.1016/j.rmed.2019.04.005. Epub 2019 Apr 17.
2 The composition of the gut microbiota throughout life, with an emphasis on early life.Microb Ecol Health Dis. 2015 Feb 2;26:26050. doi: 10.3402/mehd.v26.26050. eCollection 2015.
3 Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity. Microbiome. 2019 Mar 13;7(1):39. doi: 10.1186/s40168-019-0654-1.

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