General Information of HIF (ID: HIFM0107)
HIF Name	Glucagon-like peptide 1
HIF Synonym(s)	Glucagon-like peptide 1
HIF Classification	Cytokine (Cyt)
Molecular Function	Hormone
Description	GLP-1 stands for glucagon-like peptide, a type of hormone known as an incretin hormone that's lower than normal in people with type 2 diabetes. GLP-1 receptor agonists belong to a class of medications known as incretin mimetics that help the pancreas to release the optimal amount of insulin, a hormone that transports glucose (sugar) to tissues in the body where it can be used for energy.				[1]
Pfam	Peptide hormone (PF00123 )
Pathway	Glucagon signaling pathway (hsa04922 )
	Insulin secretion (hsa04911 )
	Neuroactive ligand-receptor interaction (hsa04080 )
	Thermogenesis (hsa04714 )
	cAMP signaling pathway (hsa04024 )
Sequence	Click here to download the HIF sequence in FASTA format
External Links
	Uniprot ID	GLUC_HUMAN

Microbe Species (MIC) Regulated by This HIF
Bifidobacterium breve (actinobacteria)			MIC00210
Description	Bifidobacterium breve is associated with the GLP-1 expression.				[2]

References
1	Is GLP-1 a hormone: Whether and When. J Diabetes Investig. 2016 Apr;7 Suppl 1(Suppl 1):50-5. doi: 10.1111/jdi.12466. Epub 2016 Mar 14.
2	The Combination of Bifidobacterium breve and Three Prebiotic Oligosaccharides Modifies Gut Immune and Endocrine Functions in Neonatal Mice. J Nutr. 2019 Feb 1;149(2):344-353. doi: 10.1093/jn/nxy248.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.