General Information of HIF (ID: HIFM0113)
HIF Name	Human Histatin 3
HIF Synonym(s)	Human Histatin 3, hst3, PB
HIF Classification	Antimicrobial peptide (AMP)
Molecular Function	Antibiotic; Antimicrobial; Fungicide
Description	human Histatin 3 has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system.				[1]
Pathway	Salivary secretion (hsa04970 )
Sequence	Click here to download the HIF sequence in FASTA format
External Links
	Uniprot ID	HIS3_HUMAN
	APD ID	AP00518

Microbe Species (MIC) Regulated by This HIF
Candida albicans (budding yeasts)			MIC00317
Description	Histatin 3 kill activity against Candida albicans by LD50s of 4.6 nmol/ml.				[2]

References
1	APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2	Human antimicrobial peptides and proteins.Pharmaceuticals (Basel). 2014 May 13;7(5):545-94. doi: 10.3390/ph7050545.

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