Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)
General Information of HIF (ID: HIFM0210) | |||||
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HIF Name |
Tryptophan 2,3-dioxygenase
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HIF Synonym(s) |
TDO, TDO2
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HIF Classification |
Checkpoint molecule (CM)
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Molecular Function |
Dioxygenase; Oxidoreductase
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Description | The TDO2 is reported to be crucial immunecheckpointmolecules. | [1] | |||
Pfam | Tryptophan 2,3-dioxygenase (PF03301 ) | ||||
Pathway | Metabolic pathways (hsa01100 ) | ||||
Tryptophan metabolism (hsa00380 ) | |||||
Sequence | Click here to download the HIF sequence in FASTA format | ||||
External Links | |||||
Uniprot ID | |||||
Microbe Species (MIC) Regulated by This HIF | |||||
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Staphylococcus aureus (firmicutes) | MIC01208 | ||||
Description | The HeLa cells expressing recombinant TDO2 were capable of inhibiting the growth of bacteria(Staphylococcus aureus). | [2] | |||
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