Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)
General Information of HIF (ID: HIFM0229) | |||||
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HIF Name |
Tumor necrosis factor receptor superfamily member 14
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HIF Synonym(s) |
TR2, HVEA, HVEM, Herpesvirus entry mediator A, CD270
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HIF Classification |
Checkpoint molecule (CM)
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Molecular Function |
Host cell receptor for virus entry; Receptor
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Description | CD270 is reported to be crucial immune modulator. | [1] | |||
Pfam | TNFR/NGFR cysteine-rich region (PF00020 ) | ||||
Pathway | Cytokine-cytokine receptor interaction (hsa04060 ) | ||||
Herpes simplex virus 1 infection (hsa05168 ) | |||||
Viral protein interaction with cytokine and cytokine receptor (hsa04061 ) | |||||
Sequence | Click here to download the HIF sequence in FASTA format | ||||
External Links | |||||
Uniprot ID | |||||
Microbe Species (MIC) Regulated by This HIF | |||||
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Citrobacter rodentium (enterobacteria) | MIC00366 | ||||
Description | Herpes virus entry mediator (HVEM) (it is also known as TNFRSF14 or CD270) expression by intestinal epithelium provides anti-inflammatory and anti-bacterial protection during Citrobacter rodentium infection correlates well. | [2] | |||
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