General Information of HIF (ID: HIFM0246)
HIF Name	Toll-like receptor 15
HIF Synonym(s)	toll-like receptor 15
HIF Classification	Toll-like receptor (TLR)
Description	Toll-like receptor 15 is an avian specific TLR				[1]

Microbe Species (MIC) Regulated by This HIF
Mycoplasma gallisepticum (mycoplasmas)			MIC00869
Description	TLR15 transcription was decreased in Mycoplasma gallisepticum Rlow-infected subjects.				[2]
Mycoplasma synoviae (mycoplasmas)			MIC00877
Description	Diacylated lipopeptide from Mycoplasma synoviae mediated TLR15 could induce innate immune responses.				[3]

References
1	Innate immunity to recombinant QseC, a bacterial adrenergic receptor, may regulate expression of virulence genes of avian pathogenic Escherichia coli.Vet Microbiol. 2014 Jun 25;171(1-2):236-41. doi: 10.1016/j.vetmic.2014.03.024. Epub 2014 Apr 2.
2	Transcriptional and Pathological Host Responses to Coinfection with Virulent or Attenuated Mycoplasma gallisepticum and Low-Pathogenic Avian Influenza A Virus in Chickens. Infect Immun. 2019 Dec 17;88(1):e00607-19. doi: 10.1128/IAI.00607-19. Print 2019 Dec 17.
3	Diacylated lipopeptide from Mycoplasma synoviae mediates TLR15 induced innate immune responses. Vet Res. 2013 Oct 17;44(1):99. doi: 10.1186/1297-9716-44-99.

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