General Information of HIF (ID: HIFM0293)
HIF Name	hGAPDH(2-32)
HIF Synonym(s)	Hgapdh(2-32)
HIF Classification	Antimicrobial peptide (AMP)
Description	hGAPDH(2-32) has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system.				[1]
External Links
	APD ID	AP02028

Microbe Species (MIC) Regulated by This HIF
Candida albicans (budding yeasts)			MIC00317
Description	The infection of Experimental Candida albicans could induce the expression of epithelial hGAPDH (2-32).				[2]
Escherichia coli (enterobacteria)			MIC00516
Description	The antifungal activities hGAPDH(2-32) with 10 g/ml is less active against Escherichia coli.				[2]

References
1	APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2	A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation.J Invest Dermatol. 2013 Jan;133(1):144-53. doi: 10.1038/jid.2012.254. Epub 2012 Jul 26.

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