Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFM0306)
HIF Name
Human neutrophil peptide-2
HIF Synonym(s)
Human Neutrophil Peptide-2, HNP-2, HNP2
HIF Classification
Antimicrobial peptide (AMP)
Description human neutrophil peptide-2 has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system. [1]
External Links
APD ID
AP00177
Microbe Species (MIC) Regulated by This HIF
         Porphyromonas gingivalis (CFB bacteria) MIC01000
             Description Overexpression of human neutrophil peptide-2(HNP2) defensins against Porphyromonas gingivalis infection of human OSCC samples and of OSCC cells (BHY line). [2]
References
1 APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2 Role of Porphyromonas gingivalis in oral squamous cell carcinoma development: A systematic review.J Periodontal Res. 2020 Jan;55(1):13-22. doi: 10.1111/jre.12691. Epub 2019 Sep 17.

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