General Information of HIF (ID: HIFM0312)
HIF Name	LL-23
HIF Synonym(s)	LL-23, LL23
HIF Classification	Antimicrobial peptide (AMP)
Description	LL-23 has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system.				[1]
External Links
	APD ID	AP00625

Microbe Species (MIC) Regulated by This HIF
Staphylococcus aureus (firmicutes)			MIC01208
Description	The LL-23 variants could kill the mprF strain of Staphylococcus aureus.				[2]

References
1	APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2	Structure, dynamics, and antimicrobial and immune modulatory activities of human LL-23 and its single-residue variants mutated on the basis of homologous primate cathelicidins.Biochemistry. 2012 Jan 17;51(2):653-64. doi: 10.1021/bi2016266. Epub 2012 Jan 6.

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