Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFM0327)
HIF Name
SgII peptide A
HIF Synonym(s)
Sgii Peptide A, Semenogelin II-derived AMP A
HIF Classification
Antimicrobial peptide (AMP)
Description SgII peptide A has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system. [1]
External Links
APD ID
AP01407
Microbe Species (MIC) Regulated by This HIF
         Streptococcus pyogenes (firmicutes) MIC01267
             Description SgII peptide A exhibited antibacterial activity in CFU assay in a concentration of 0.32 M against Streptococcus pyogenes. [2]
References
1 APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2 The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins.J Immunol. 2008 Sep 1;181(5):3413-21. doi: 10.4049/jimmunol.181.5.3413.

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