General Information of HIF (ID: HIFM0329)
HIF Name	secreted type IIA Phospholipase A2
HIF Synonym(s)	Spla2-IIA, sPLA2-IIA
HIF Classification	Antimicrobial peptide (AMP)
Description	sPLA2-IIA has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system.				[1]
External Links
	APD ID	AP02537

Microbe Species (MIC) Regulated by This HIF
Pseudomonas aeruginosa (gamma-proteobacteria)			MIC01054
Description	Pseudomonas aeruginosa laboratory strains and isolates could induce sPLA2-IIA expression.				[2]

References
1	APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2	Pseudomonas aeruginosa eradicates Staphylococcus aureus by manipulating the host immunity.Nat Commun. 2014 Oct 7;5:5105. doi: 10.1038/ncomms6105.

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