Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFP0001)
HIF Name	Aryl Hydrocarbon Receptor signaling pathway/Cytochrome P450 Family 1 Subfamily A Member 1 signaling pathway
HIF Synonym(s)	AhR-CYP1A1 pathway, AHR/CYP1A1 signaling pathway
HIF Classification	Signaling pathway (SP)
Description	Signaling pathway aryl hydrocarbon receptor (AhR) cytochrome P450 CYP1A1 is involved in the metabolism of xenobiotics, as well as in homeostasis of endogenous compounds such as eicosanoids or retinoids.	[1]

Microbe Species (MIC) Regulated by This HIF
Enterococcus gallinarum (firmicutes)		MIC00550
Description	Enterococcus gallinarum is associated with the activation of AhR-CYP1A1 pathway.		[2]

References
1	Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. Toxicol Lett. 2013 Jul 31;221(1):1-8. doi: 10.1016/j.toxlet.2013.05.007. Epub 2013 Jun 2.
2	Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science. 2018 Mar 9;359(6380):1156-1161. doi: 10.1126/science.aar7201.

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