General Information of HIF (ID: HIFP0006)
HIF Name	Dectin-1 signaling pathway
HIF Synonym(s)	dectin-1, Dectin-1 signaling pathway
HIF Classification	Signaling pathway (SP)
Description	Dectin-1 is a recently discovered pattern-recognition receptor that plays an important role in antifungal innate immunity.				[1]

Microbe Species (MIC) Regulated by This HIF
Mycobacteroides abscessus (actinobacteria)			MIC00845
Description	Mycobacterium abscessus activates the macrophage innate immune response via a physical and functional interaction between TLR2 and dectin-1.				[2]

References
1	Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells.Nat Commun. 2016 Aug 5;7:12368. doi: 10.1038/ncomms12368.
2	Host immune response to rapidly growing mycobacteria, an emerging cause of chronic lung disease. Am J Respir Cell Mol Biol. 2010 Oct;43(4):387-93. doi: 10.1165/rcmb.2009-0276TR. Epub 2010 Jan 15.

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