General Information of HIF (ID: HIFP0007)
HIF Name
Extracellular signal-regulated kinase signaling pathway
HIF Synonym(s)
ERK, ERK signaling pathway
HIF Classification
Signaling pathway (SP)
Description The extracellular-signal-regulated kinase (ERK) pathway is one of the major signaling cassettes of the mitogen activated protein kinase (MAPK) signaling pathway. [1]
Microbe Species (MIC) Regulated by This HIF
         Klebsiella pneumoniae (enterobacteria) MIC01405
             Description At the species level, Klebsiella pneumoniae is associated with ERK. [2]
References
1 The expression of ER, PR in endometrial cancer and analysis of their correlation with ERK signaling pathway.Cancer Biomark. 2017 Dec 12;21(1):145-149. doi: 10.3233/CBM-170457.
2 Pseudomonas aeruginosa and Klebsiella pneumoniae Adaptation to Innate Immune Clearance Mechanisms in the Lung. J Innate Immun. 2018;10(5-6):442-454. doi: 10.1159/000487515. Epub 2018 Apr 4.

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