Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFP0018)
HIF Name	Interleukin 1 signaling pathway
HIF Synonym(s)	interleukin 1 (IL-1) pathway, Interleukin 1 signaling pathway
HIF Classification	Signaling pathway (SP)
Description	Interleukin-1 (IL-1) is a pleiotropic cytokine that can induce several cellular signal transduction pathways.	[1]

Microbe Species (MIC) Regulated by This HIF
Acinetobacter baumannii (gamma-proteobacteria)		MIC00016
Description	Acinetobacter baumannii could trigger the IL-1Beta pathway.		[2]

References
1	Mucus obstruction and inflammation in early cystic fibrosis lung disease: Emerging role of the IL-1 signaling pathway.Pediatr Pulmonol. 2019 Nov;54 Suppl 3:S5-S12. doi: 10.1002/ppul.24462.
2	Caspase-11 Plays a Protective Role in Pulmonary Acinetobacter baumannii Infection. Infect Immun. 2017 Sep 20;85(10):e00350-17. doi: 10.1128/IAI.00350-17. Print 2017 Oct.

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