General Information of HIF (ID: HIFP0027)
HIF Name	NETosis signaling pathway
HIF Synonym(s)	NETosis, NETosis signaling pathway
HIF Classification	Signaling pathway (SP)
Description	NETosis is a process whereby neutrophils release chromatin into the surrounding extracellular matrix to form neutrophil extracellular traps (NETs).				[1]

Microbe Species (MIC) Regulated by This HIF
Chlamydia trachomatis (chlamydias)			MIC00344
Description	At the species level, Chlamydia trachomatis is associated with NETosis				[2]

References
1	Potent NETosis inducers do not show synergistic effects in vitro.Cent Eur J Immunol. 2019;44(1):51-58. doi: 10.5114/ceji.2019.84017. Epub 2019 Apr 15.
2	Chlamydia trachomatis regulates innate immune barrier integrity and mediates cytokine and antimicrobial responses in human uterine ECC-1 epithelial cells. Am J Reprod Immunol. 2017 Dec;78(6). doi: 10.1111/aji.12764. Epub 2017 Sep 16.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.