General Information of MIC (ID: MIC00154)
MIC Name Bacteroides dorei (CFB bacteria)
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Bacteroidaceae
Genus: Bacteroides
Species: Bacteroides dorei
Oxygen Sensitivity Anaerobe
Microbial Metabolism Saccharolytic; Fermentative
Gram Negative
Host Relationship Commensal
Genome Size (bp) 5243219
Description Bacteroides dorei is an anaerobic, Gram-negative bacterium. Bacteroides dorei plays an important role in the normal function of the intestinal system of both human and animal species. Along with many beneficial functions, it come with a few pathogenic functions that could take place as well. It has also been associated withCoronary artery disease.
External Links Taxonomy ID
357276
Genome Assembly ID
ASM15607v1
GOLD Organism ID
Go0003531
Disease Relevance
          Diseases of coronary artery  [ICD-11: BA8Z]
             Description Fecal lipopolysaccharide levels in patients with Coronary artery disease were significantly higher and negatively correlated with the abundance of Bacteroides dorei. [1]
          Parkinsonism  [ICD-11: 8A00]
             Description Bacteroides dorei was reduced in patients with parkinsons disease. [2]
Host Immune Factors (HIFs)
          Neutrophils
             HIF ID HIFC0029 HIF Info       Class Granulocytes (Gra)
             Description Bacteroides dorei at neutrophil recovery was positively correlated with subsequent acute severe graft-versus-host disease. [3]
Environmental Factor(s)
             Disbiome ID
      767
             gutMDisorder ID
      gm0081
References
1 Bacteroides vulgatus and Bacteroides dorei Reduce Gut Microbial Lipopolysaccharide Production and Inhibit Atherosclerosis. Circulation. 2018 Nov 27;138(22):2486-2498. doi: 10.1161/CIRCULATIONAHA.118.033714.
2 Analysis of Gut Microbiota in Patients with Parkinson's Disease. Bull Exp Biol Med. 2017 Apr;162(6):734-737. doi: 10.1007/s10517-017-3700-7. Epub 2017 Apr 20.
3 Stool Microbiota at Neutrophil Recovery Is Predictive for Severe Acute Graft vs Host Disease After Hematopoietic Cell Transplantation.Clin Infect Dis. 2017 Nov 29;65(12):1984-1991. doi: 10.1093/cid/cix699.

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