General Information of MIC (ID: MIC00155)
MIC Name	Bacteroides eggerthii (CFB bacteria)
Body Site	Gut
Lineage	Kingdom: Bacteria Phylum: Bacteroidetes Class: Bacteroidia Order: Bacteroidales Family: Bacteroidaceae Genus: Bacteroides Species: Bacteroides eggerthii
Oxygen Sensitivity	Anaerobe
Microbial Metabolism	Saccharolytic; Fermentative
Gram	Negative
Host Relationship	Commensal
Genome Size (bp)	4157980
Description	Bacteroides eggerthii is a species of obligately anaerobic, Gram-negative, rod shaped bacteria assigned to the phylum Bacteroidetes. It is commensal and part of the normal flora of the human gastrointestinal tract, but may become pathogenic in other body regions. It has also been associated with Inflammatory bowel disease.
External Links	Taxonomy ID	28111
	Genome Assembly ID	ASM15581v1
	GOLD Organism ID	Go0003532
Disease Relevance
Chronic kidney disease  [ICD-11: GB61]
Description	Bacteroides eggerthii was identified to be highly correlated with the stages of CKD(Chronic kidney disease).				[1]
Inflammatory bowel disease  [ICD-11: DD72]
Description	Bacteroides eggerthii was a colitis-promoting species.				[2]
Obesity  [ICD-11: 5B81]
Description	Bacteroides eggerthii abundance was significantly high in obese children.				[3]

Host Genetic Factors (HGFs)
SMARCAD1
HGF ID	HGF2342	HGF Info	Class	Copy Number Variation: Gene Deletion (CNV-GDe)
Description	The deletion of SMARCAD1 was significantly associated with a decrease of Bacteroides eggerthii (p-value<0.05).				[4]

Environmental Factor(s)
Disbiome ID			592
gutMDisorder ID			gm0077

References
1	Gut Microbiota as Diagnostic Tools for Mirroring Disease Progression and Circulating Nephrotoxin Levels in Chronic Kidney Disease: Discovery and Validation Study. Int J Biol Sci. 2020 Jan 1;16(3):420-434. doi: 10.7150/ijbs.37421. eCollection 2020.
2	Pglyrp-Regulated Gut Microflora Prevotella falsenii, Parabacteroides distasonis and Bacteroides eggerthii Enhance and Alistipes finegoldii Attenuates Colitis in Mice. PLoS One. 2016 Jan 4;11(1):e0146162. doi: 10.1371/journal.pone.0146162. eCollection 2016.
3	Composition of gut microbiota in obese and normal-weight Mexican school-age children and its association with metabolic traits. Pediatr Obes. 2018 Jun;13(6):381-388. doi: 10.1111/ijpo.12262. Epub 2017 Dec 5.
4	Smarcad1 mediates microbiota-induced inflammation in mouse and coordinates gene expression in the intestinal epithelium.Genome Biol. 2020 Mar 11;21(1):64. doi: 10.1186/s13059-020-01976-7.

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