General Information of MIC (ID: MIC00284)
MIC Name Burkholderia multivorans (beta-proteobacteria)
MIC Synonyms Burkholderia cepacia genomovar II
Body Site Lung
Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Burkholderiales
Family: Burkholderiaceae
Genus: Burkholderia
Species: Burkholderia multivorans
Oxygen Sensitivity Aerobe
Microbial Metabolism Non-glucose fermenting
Gram Negative
Host Relationship Opportunistic pathogen
Genome Size (bp) 7281867
No. of Coding Genes 5792
No. of Non-Coding Genes 67
No. of Small Non-Coding Genes 67
No. of Gene Transcripts 5859
No. of Base Pairs 6668882
Description Burkholderia multivorans formally known as Pseudomonas cepacia and Burkholderia cepacia genomovar II, is an aerobic, Gram-negative bacillus and a member of the Burkholderia cepacia complex.
External Links Taxonomy ID
87883
Genome Assembly ID
D2095.1
GOLD Organism ID
Go0003118
Disease Relevance
          Cystic fibrosis  [ICD-11: CA25]
             Description Burkholderia multivorans was capable of suppressing growth and virulence of co-colonizing CF(Cystic fibrosis) pathogens. [1]
Host Immune Factors (HIFs)
          Interleukin-1 beta
             HIF ID HIFM0138 HIF Info       Class Cytokine (Cyt)
             Description The level of IL-1beta in Burkholderia multivorans-challenged mice was significantly higher (P < 0.0001). [2]
Environmental Factor(s)
             Disbiome ID
      371
             gutMDisorder ID
      gm0131
             aBiofilm Organism
      Burkholderia multivorans
References
1 Inhibition of co-colonizing cystic fibrosis-associated pathogens by Pseudomonas aeruginosa and Burkholderia multivorans. Microbiology. 2014 Jul;160(Pt 7):1474-1487. doi: 10.1099/mic.0.074203-0. Epub 2014 Apr 30.
2 Persistence of Burkholderia multivorans within the pulmonary macrophage in the murine lung. Infect Immun. 2004 Oct;72(10):6142-7. doi: 10.1128/IAI.72.10.6142-6147.2004.

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