Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00394)
MIC Name Blautia coccoides (firmicutes)
MIC Synonyms Clostridium coccoides
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Clostridiales
Family: Lachnospiraceae
Genus: Blautia
Species: Blautia coccoides
Oxygen Sensitivity Obligate anaerobe
Microbial Metabolism Fermentative
Gram Positive
Host Relationship Commensal
Description Blautia coccoides is one of the major intestinal microbes often found in human faecal samples. It is a strict anaerobe and Gram-positive bacterium recently reclassified from Clostridium.
External Links Taxonomy ID
1532
Genome Assembly ID
ASM222155v2
GOLD Organism ID
Go0468474
Disease Relevance
          Coeliac disease  [ICD-11: DA95]
             Description Clostridium coccoides is downregulated in disease expression of celiac disease. [1]
          Inflammatory bowel disease  [ICD-11: DD72]
             Description Clostridium coccoides is downregulated in disease expression of inflammatory bowel disease. [1]
          Irritable bowel syndrome  [ICD-11: DD91]
             Description Irritable bowel syndrome was associated with Clostridium coccoides infection. [2]
          Parkinsonism  [ICD-11: 8A00]
             Description The number of Clostridium coccoides was low in Parkinsons disease. [3]
Host Immune Factors (HIFs)
          Immunoglobulin E
             HIF ID HIFM0271 HIF Info       Class Immunoglobulin (Ig)
             Description IgE immune responses was associated with Clostridium coccoides. [4]
Environmental Factor(s)
             Disbiome ID
      239
             gutMDisorder ID
      gm0198
References
1 The impact of the gut microbiota on human health: an integrative view. Cell. 2012 Mar 16;148(6):1258-70. doi: 10.1016/j.cell.2012.01.035.
2 Pathogenic factors involved in the development of irritable bowel syndrome: focus on a microbial role. Infect Dis Clin North Am. 2010 Dec;24(4):961-75, ix. doi: 10.1016/j.idc.2010.07.005.
3 Intestinal Dysbiosis and Lowered Serum Lipopolysaccharide-Binding Protein in Parkinson's Disease. PLoS One. 2015 Nov 5;10(11):e0142164. doi: 10.1371/journal.pone.0142164. eCollection 2015.
4 A synbiotic-containing amino-acid-based formula improves gut microbiota in non-IgE-mediated allergic infants.Pediatr Res. 2018 Mar;83(3):677-686. doi: 10.1038/pr.2017.270. Epub 2017 Dec 6.

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