General Information of MIC (ID: MIC00439)
MIC Name	Coprobacillus cateniformis
MIC Synonyms	Coprobacillus catenaformis
Body Site	Gut
Lineage	Kingdom: Bacteria Phylum: Firmicutes Class: Erysipelotrichia Order: Erysipelotrichales Family: Erysipelotrichaceae Genus: Coprobacillus Species: Coprobacillus cateniformis
Oxygen Sensitivity	Obligate anaerobe
Microbial Metabolism	Saccharolytic; Fermentative
Gram	Positive
Description	Coprobacillus cateniformis is a bacterium from the genus of Coprobacillus which has been isolated from human feces in Japan.
External Links	Taxonomy ID	100884
	Genome Assembly ID	ASM976758v1
	GOLD Organism ID	Go0477446
Disease Relevance
Autoimmune liver disease  [ICD-11: DB96]
Description	Coprobacillus was associated with PSC-IBD(primary sclerosing cholangitis-inflammatory bowel disease), but not with isolated PSC.				[1]
Rheumatoid arthritis  [ICD-11: FA20]
Description	Coprobacillus was associated with genetic variants in Rheumatoid Arthritis.				[2]
Ulcerative colitis  [ICD-11: DD71]
Description	Coprobacillus was associated with PSC-IBD(primary sclerosing cholangitis-inflammatory bowel disease), but not with isolated PSC.				[1]

Host Immune Factors (HIFs)
Interleukin-1 beta
HIF ID	HIFM0138	HIF Info	Class	Cytokine (Cyt)
Description	Coprobacillus is associated with IL-1beta expression.				[3]

Environmental Factor(s)
Disbiome ID			676
gutMDisorder ID			gm0222

References
1	Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis. World J Gastroenterol. 2017 Jul 7;23(25):4548-4558. doi: 10.3748/wjg.v23.i25.4548.
2	M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases. bioRxiv, 2019.
3	Sex and strain dependent differences in mucosal immunology and microbiota composition in mice. Biol Sex Differ. 2018 Jun 18;9(1):26. doi: 10.1186/s13293-018-0186-6.

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