| General Information of MIC (ID: MIC00477) |
| MIC Name |
Deferribacteres (bacteria)
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| MIC Synonyms |
Flexistipes group
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| Body Site |
Gut
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| Lineage |
Kingdom: Bacteria
Phylum: Deferribacteres
Class: Deferribacteres
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| Oxygen Sensitivity |
Obligate anaerobe
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| Microbial Metabolism |
Fermentative
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| Gram |
Negative
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| Host Relationship |
Pathogen
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| Description |
The Deferribacteres is a family of Gram-negative bacteria which makes energy by anaerobic respiration.
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| External Links |
Taxonomy ID |
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| Disease Relevance |
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| Hyperinsulinemia [ICD-11: 5A4Y] |
| Description |
Deferribacteres was associated with hyperinsulinemia. |
[1] |
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| Host Genetic Factors (HGFs) |
| SHANK3 |
| HGF ID |
HGF2351 |
HGF Info
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Class |
Copy Number Variation: Gene Deletion (CNV-GDe) |
| Description |
The deletion of SHANK3 has been significantly associated with the decreased abundance of Deferribacteres (p-value<0.001). |
[2] |
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| Environmental Factor(s) |
| gutMDisorder ID |
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| References |
| 1 |
Maternal exercise before and during pregnancy alleviates metabolic dysfunction associated with high-fat diet in pregnant mice, without significant changes in gut microbiota. Nutr Res. 2019 Sep;69:42-57. doi: 10.1016/j.nutres.2019.08.002. Epub 2019 Aug 8.
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| 2 |
Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model.Int J Mol Sci. 2019 Apr 30;20(9):2134. doi: 10.3390/ijms20092134.
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