General Information of HGF (ID: HGF2351)
HGF Name	SHANK3
HGF Synonym(s)	PSAP2, SCZD15, PROSAP2, SPANK-2, DEL22q13.3, SH3 and multiple ankyrin repeat domains 3
Source	Homo sapiens
HGF Classification	Copy Number Variation: Gene Deletion (CNV-GDe)
Gene Location	chr22
Gene Start Site	50674415	Gene End Site		50733298
Strand	Forward (+)
External Links
	Ensembl ID	ENSG00000251322

Microbe Species (MIC) Regulated by This HGF
Actinobacteria (actinobacteria)			MIC00025
Description	The deletion of SHANK3 has been significantly associated with the decreased amount of Actinobacteria (p-value<0.001).				[1]
Deferribacteres (bacteria)			MIC00477
Description	The deletion of SHANK3 has been significantly associated with the decreased abundance of Deferribacteres (p-value<0.001).				[1]
Eggerthella lenta (actinobacteria)			MIC00520
Description	The deletion of SHANK3 has been significantly associated with the decreased amount of Eggerthella (p-value<0.001).				[2]
Enterorhabdus (actinobacteria)			MIC01969
Description	The deletion of SHANK3 has been significantly associated with the increased amount of Enterorhabdus (p-value<0.05).				[3]
Paraeggerthella (actinobacteria)			MIC00956
Description	The deletion of SHANK3 has been significantly associated with the decreased amount of Paraeggerthella (p-value<0.05).				[4]
Proteobacteria (proteobacteria)			MIC01037
Description	The deletion of SHANK3 has been significantly associated with the decreased amount of Proteobacteria (p-value<0.05).				[1]
Tenericutes (bacteria)			MIC01308
Description	The deletion of SHANK3 has been significantly associated with the increased amount of Tenericutes (p-value<0.001).				[1]
Verrucomicrobia (verrucomicrobia)			MIC01368
Description	The deletion of SHANK3 has been significantly associated with the decreased amount of Verrucomicrobia (p-value<0.001).				[1]

References
1	Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model.Int J Mol Sci. 2019 Apr 30;20(9):2134. doi: 10.3390/ijms20092134.
2	Micron-Size White Bamboo Fibril-Based Silane Cellulose Aerogel: Fabrication and Oil Absorbent Characteristics.Materials (Basel). 2019 Apr 30;12(9):1407. doi: 10.3390/ma12091407.
3	Difference in Long-Term Trends in COPD Mortality between China and the U.S., 19922017: An AgePeriodCohort Analysis.Int J Environ Res Public Health. 2019 Apr 30;16(9):1529. doi: 10.3390/ijerph16091529.
4	A Bird's-Eye View of Chronic Unilateral Conjunctivitis: Remember about Chlamydia psittaci.Microorganisms. 2019 Apr 30;7(5):118. doi: 10.3390/microorganisms7050118.

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