Details of Microbe Species (MIC)

General Information of MIC (ID: MIC01308)
MIC Name Tenericutes (bacteria)
MIC Synonyms Mollicutaeota; Mollicutota
Body Site Oral Cavity
Lineage Kingdom: Bacteria
Phylum: Tenericutes
Oxygen Sensitivity Facultative anaerobe; Aerobe
Microbial Metabolism Saccharolytic; Respiratory or Fermentative
Gram Negative
Description Tenericutes is a phylum of bacteria that contains the class Mollicutes and that presented almost the same distribution of Spirochaeta.
External Links Taxonomy ID
544448
Host Genetic Factors (HGFs)
          SHANK3
             HGF ID HGF2351 HGF Info       Class Copy Number Variation: Gene Deletion (CNV-GDe)
             Description The deletion of SHANK3 has been significantly associated with the increased amount of Tenericutes (p-value<0.001). [1]
          rs6925614
             HGF ID HGF1832 HGF Info       Class Single Nucleotide Polymorphism: Missense variant (SNP-MV)
             Description The rs6925614 SNP was significantly associated with the abundance of Tenericutes (p-value=2.19E-08). [2]
          rs516246
             HGF ID HGF1582 HGF Info       Class Single Nucleotide Polymorphism: Non coding transcript variant (SNP-NCTV)
             Description The rs516246 SNP was significantly associated with the abundance of Tenericutes (p-value=0.01175). [3]
          rs4883972
             HGF ID HGF2214 HGF Info       Class Single Nucleotide Polymorphism (SNP)
             Description The rs4883972 SNP was significantly associated with the abundance of gut microbiota Tenericutes (p-value<5.00E-05). [4]
          rs12311520
             HGF ID HGF2246 HGF Info       Class Single Nucleotide Polymorphism (SNP)
             Description The rs12311520 SNP was significantly associated with the abundance of gut microbiota Tenericutes (p-value<5.00E-05). [4]
Environmental Factor(s)
             Disbiome ID
      534
             gutMDisorder ID
      gm0637
References
1 Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model.Int J Mol Sci. 2019 Apr 30;20(9):2134. doi: 10.3390/ijms20092134.
2 Host genetic variation impacts microbiome composition across human body sites.Genome Biol. 2015 Sep 15;16(1):191. doi: 10.1186/s13059-015-0759-1.
3 FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects.Gut Microbes. 2018 Jul 4;9(4):357-368. doi: 10.1080/19490976.2018.1445956. Epub 2018 Apr 27.
4 Assessing the Relationship Between Gut Microbiota and Bone Mineral Density.Front Genet. 2020 Jan 31;11:6. doi: 10.3389/fgene.2020.00006. eCollection 2020.

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