| General Information of MIC (ID: MIC00479) |
| MIC Name |
Delftia acidovorans (beta-proteobacteria)
|
| MIC Synonyms |
Pseudomonas acidovorans
|
| Body Site |
Blood
|
| Lineage |
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Burkholderiales
Family: Comamonadaceae
Genus: Delftia
Species: Delftia acidovorans
|
| Oxygen Sensitivity |
Facultative anaerobe
|
| Microbial Metabolism |
Fermentative
|
| Gram |
Negative
|
| Genome Size (bp) |
6767514
|
| No. of Coding Genes |
6043
|
| No. of Non-Coding Genes |
71
|
| No. of Small Non-Coding Genes |
71
|
| No. of Gene Transcripts |
6114
|
| No. of Base Pairs |
6777458
|
| Description |
Delftia acidovorans is an aerobic, nonfermenting Gram-negative bacillus. It is usually a nonpathogenic environmental organism and is rarely clinically significant.
|
| External Links |
Taxonomy ID |
|
| Genome Assembly ID |
|
| GOLD Organism ID |
|
| Disease Relevance |
|---|
| Type 1 diabetes mellitus [ICD-11: 5A10] |
| Description |
Type 1 diabetes was associated with Delftia acidovorans infection. |
[1] |
|
|
|
|
|
|
| Host Genetic Factors (HGFs) |
| rs62022890 |
| HGF ID |
HGF2187 |
HGF Info
|
Class |
Single Nucleotide Polymorphism (SNP) |
| Description |
The rs62022890 SNP in mucosal immunity pathways influences the abundance of Delftia in the upper airway (p-value=6.08E-07). |
[2] |
| rs1986228 |
| HGF ID |
HGF2188 |
HGF Info
|
Class |
Single Nucleotide Polymorphism (SNP) |
| Description |
The rs1986228 SNP in mucosal immunity pathways influences the abundance of Delftia in the upper airway (p-value=7.60E-07). |
[2] |
| rs12437768 |
| HGF ID |
HGF1635 |
HGF Info
|
Class |
Single Nucleotide Polymorphism: Intron variant (SNP-IV) |
| Description |
The rs12437768 SNP in mucosal immunity pathways influences the abundance of Delftia in the upper airway (p-value=9.77E-07). |
[2] |
|
|
|
|
|
|
| Host Immune Factors (HIFs) |
| Immunoglobulin G |
| HIF ID |
HIFM0270 |
HIF Info
|
Class |
Immunoglobulin (Ig) |
| Description |
Delftia could be preferentially enriched in the IgG-targeted fraction of the microbiota. |
[3] |
|
|
|
|
|
|
| Environmental Factor(s) |
| Disbiome ID |
|
| gutMDisorder ID |
|
|
|
|
|
|
|
| References |
| 1 |
Systemic exposure to Pseudomonal bacteria: a potential link between type 1 diabetes and chronic inflammation. Acta Diabetol. 2013 Jun;50(3):351-61. doi: 10.1007/s00592-012-0421-2. Epub 2012 Aug 5.
|
| 2 |
Host genetic variation in mucosal immunity pathways influences the upper airway microbiome.Microbiome. 2017 Feb 1;5(1):16. doi: 10.1186/s40168-016-0227-5.
|
| 3 |
The antibody/microbiota interface in health and disease.Mucosal Immunol. 2020 Jan;13(1):3-11. doi: 10.1038/s41385-019-0192-y. Epub 2019 Aug 14.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.
