Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00505)
MIC Name Dialister invisus (firmicutes)
Body Site Oral Cavity
Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Negativicutes
Order: Veillonellales
Family: Veillonellaceae
Genus: Dialister
Species: Dialister invisus
Oxygen Sensitivity Obligate anaerobe
Microbial Metabolism Fermentative; Asaccharolytic
Gram Negative
Host Relationship Pathogen
Genome Size (bp) 1895860
Description Dialister invisus is an obligate anaerobic, Gram negative non-motile bacteria. As D. invisus has been associated with marginal periodontitis, caries, halitosis and apical periodontitis and is commonly isolated from endodontic infections it is consider a significant human pathogen.
External Links Taxonomy ID
218538
Genome Assembly ID
ASM16005v1
GOLD Organism ID
Go0003470
Disease Relevance
          Periapical periodontitis  [ICD-11: DA09]
             Description Dialister invisus was associated with chronic apical abscesses. [1]
          Periapical periodontitis  [ICD-11: DA09]
             Description Dialister invisus was associated with apical periodontitis. [2]
          Periodontal disease  [ICD-11: DA0C]
             Description Dialister invisus was associated with marginal periodontitis. [3]
Host Genetic Factors (HGFs)
          rs1889714
             HGF ID HGF1579 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs1889714 SNP was significantly associated with the abundance of Dialister invisus (p-value=4.43815E-05). [4]
Host Immune Factors (HIFs)
          CD8+ T cells
             HIF ID HIFC0073 HIF Info       Class T cells (TCs)
             Description Dialister invisus is associated with CD8+ T cells responses. [5]
Environmental Factor(s)
             Disbiome ID
      21
             gutMDisorder ID
      gm0263
References
1 New bacterial composition in primary and persistent/secondary endodontic infections with respect to clinical and radiographic findings. J Endod. 2014 May;40(5):670-7. doi: 10.1016/j.joen.2013.10.005. Epub 2013 Nov 19.
2 Comparison of the in vivo antimicrobial effectiveness of sodium hypochlorite and chlorhexidine used as root canal irrigants: a molecular microbiology study. J Endod. 2011 Feb;37(2):143-50. doi: 10.1016/j.joen.2010.11.006.
3 Frequency and levels of candidate endodontic pathogens in acute apical abscesses as compared to asymptomatic apical periodontitis. PLoS One. 2018 Jan 2;13(1):e0190469. doi: 10.1371/journal.pone.0190469. eCollection 2018.
4 The effect of host genetics on the gut microbiome.Nat Genet. 2016 Nov;48(11):1407-1412. doi: 10.1038/ng.3663. Epub 2016 Oct 3.
5 Gut microbiome in type 1 diabetes: A comprehensive review. Diabetes Metab Res Rev. 2018 Oct;34(7):e3043. doi: 10.1002/dmrr.3043. Epub 2018 Jul 17.

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