General Information of MIC (ID: MIC00616)
MIC Name	Fusobacterium necrophorum (fusobacteria)
MIC Synonyms	Bacillus necrophorus
Body Site	Oral Cavity
Lineage	Kingdom: Bacteria Phylum: Fusobacteria Class: Fusobacteriia Order: Fusobacteriales Family: Fusobacteriaceae Genus: Fusobacterium Species: Fusobacterium necrophorum
Oxygen Sensitivity	Obligate anaerobe
Microbial Metabolism	Saccharolytic; Fermentative; Proteolytic
Gram	Negative
Host Relationship	Pathogen
Genome Size (bp)	2110802
Description	Fusobacterium necrophorum is an anaerobic, Gram negative, non-sporeforming, non-motile bacterium. The bacteria is responsible for Lemierre's syndrome and other medical problems.
External Links	Taxonomy ID	859
	Genome Assembly ID	ASM19613v1
	GOLD Organism ID	Go0004509
Disease Relevance
Dermatitis and eczema  [ICD-11: EA80]
Description	Fusobacterium necrophorum was present in CODD (Contagious ovine digital dermatitis) lesions.				[1]

Host Immune Factors (HIFs)
Macrophages
HIF ID	HIFC0020	HIF Info	Class	Macrophages (Mac)
Description	Fusobacterium necrophorum cells were mainly sequestered in phagocytic vacuoles in the cytoplasni of macrophages. And abscesses during early Fusobacterium necrophorum infection contained more macrophages.				[2]

Environmental Factor(s)
Disbiome ID			442
gutMDisorder ID			gm0344

References
1	High-level association of bovine digital dermatitis Treponema spp. with contagious ovine digital dermatitis lesions and presence of Fusobacterium necrophorum and Dichelobacter nodosus. J Clin Microbiol. 2015 May;53(5):1628-38. doi: 10.1128/JCM.00180-15. Epub 2015 Mar 4.
2	Hepatic lesions and bacterial changes in mice during infection of Fusobacterium necrophorum. Can J Microbiol. 1977 Oct;23(10):1465-77. doi: 10.1139/m77-215.

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