Details of Microbe Species (MIC)

General Information of MIC (ID: MIC01057)
MIC Name Pseudomonas mendocina (gamma-proteobacteria)
Body Site Ocular Surface
Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Pseudomonadales
Family: Pseudomonadaceae
Genus: Pseudomonas
Species: Pseudomonas mendocina
Oxygen Sensitivity Aerobe
Microbial Metabolism Nonfermentative; Nitrogen cycle
Gram Negative
Genome Size (bp) 5072807
No. of Coding Genes 4937
No. of Non-Coding Genes 83
No. of Small Non-Coding Genes 83
No. of Gene Transcripts 5020
No. of Base Pairs 5422981
Description Pseudomonas mendocina is an aerobic, Gram negative, polar monotrichous flagellated, rod shaped bacterium. It can cause opportunistic nosocomial infections, such as infective endocarditis and spondylodiscitis, although cases are very rare.
External Links Taxonomy ID
300
Genome Assembly ID
ASM72510v2
GOLD Organism ID
Go0005310
Disease Relevance
          Acquired immunodeficiency syndrome  [ICD-11: 1C62]
             Description Pseudomonas mendocina was associated with acquired immunodeficiency syndrome. [1]
          Infectious endocarditis  [ICD-11: BB40]
             Description Pseudomonas mendocina was associated with endocarditis. [2]
          Meningococcal disease  [ICD-11: 1C1C]
             Description Pseudomonas mendocina was associated with bacteraemia. [1]
          Spondyloarthritis  [ICD-11: FA92]
             Description Pseudomonas mendocina can cause spondylodiscitis, although cases are very rare. [3]
          Type 2 diabetes mellitus  [ICD-11: 5A11]
             Description Pseudomonas mendocina was associated with type 2 diabetes. [4]
Host Immune Factors (HIFs)
          P38 signaling pathway
             HIF ID HIFP0031 HIF Info       Class Signaling pathway (SP)
             Description Pseudomonas mendocina depended on weak induction of immune genes regulated by the p38 MAPK pathway. [5]
Environmental Factor(s)
             Disbiome ID
      319
             gutMDisorder ID
      gm0550
References
1 Pseudomonas Mendocina Bacteremia: A Case Study and Review of Literature. Am J Case Rep. 2019 Apr 5;20:453-458. doi: 10.12659/AJCR.914360.
2 Pseudomonas mendocina native valve infective endocarditis: a case report.J Med Case Rep. 2016 Oct 4;10(1):275. doi: 10.1186/s13256-016-1057-6.
3 Pseudomonas mendocina spondylodiscitis: a case report and literature review. Scand J Infect Dis. 2005;37(11-12):950-3. doi: 10.1080/00365540500263177.
4 Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis. Nat Commun. 2017 Jun 6;8:15393. doi: 10.1038/ncomms15393.
5 Association with soil bacteria enhances p38-dependent infection resistance in Caenorhabditis elegans. Infect Immun. 2013 Feb;81(2):514-20. doi: 10.1128/IAI.00653-12. Epub 2012 Dec 10.

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