| General Information of MIC (ID: MIC01138) |
| MIC Name |
Ruminococcus lactaris (firmicutes)
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| Body Site |
Gut
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| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Clostridiales
Family: Lachnospiraceae
Genus: Mediterraneibacter
Species: Ruminococcus lactaris
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| Oxygen Sensitivity |
Anaerobe
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| Microbial Metabolism |
Saccharolytic; Fermentative
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| Gram |
Positive
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| Host Relationship |
Commensal
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| Genome Size (bp) |
2729735
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| Description |
Ruminococcus lactaris is an anaerobe, Gram positive bacterium.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| Host Genetic Factors (HGFs) |
| rs696217 |
| HGF ID |
HGF1758 |
HGF Info
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Class |
Single Nucleotide Polymorphism: Intron variant (SNP-IV) |
| Description |
The variant gene GHRL of innate immunity rs696217 is significantly associated with the abundance of gut micriobiota Ruminococcus lactaris (p-value=0.0006). |
[1] |
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| Host Immune Factors (HIFs) |
| Signal transducer and activator of transcription 3 signaling pathway |
| HIF ID |
HIFP0038 |
HIF Info
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Class |
Signaling pathway (SP) |
| Description |
At the species level, Ruminococcus lactaris is associated with STAT3. |
[2] |
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| Environmental Factor(s) |
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| References |
| 1 |
Variants in genes of innate immunity, appetite control and energy metabolism are associated with host cardiometabolic health and gut microbiota composition.Gut Microbes. 2020 May 3;11(3):556-568. doi: 10.1080/19490976.2019.1619440. Epub 2019 Jun 3.
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| 2 |
Roseburia intestinalis supernatant ameliorates colitis induced in mice by regulating the immune response. Mol Med Rep. 2019 Aug;20(2):1007-1016. doi: 10.3892/mmr.2019.10327. Epub 2019 Jun 4.
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