Details of Microbe Species (MIC)

General Information of MIC (ID: MIC01363)
MIC Name Veillonella atypica (firmicutes)
MIC Synonyms Veillonella parvula subsp. atypica
Body Site Oral Cavity
Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Negativicutes
Order: Veillonellales
Family: Veillonellaceae
Genus: Veillonella
Species: Veillonella atypica
Oxygen Sensitivity Obligate anaerobe
Microbial Metabolism Saccharolytic; Fermentative
Gram Negative
Host Relationship Commensal
Genome Size (bp) 2095053
No. of Coding Genes 1973
No. of Non-Coding Genes 48
No. of Small Non-Coding Genes 48
No. of Gene Transcripts 2021
No. of Base Pairs 2095053
Description Veillonella atypica is an obligately anaerobic, Gram negative bacterium. It is a type of bacteria found in the guts of elite athletes, but not in sedentary people, may be transformed into a probiotic that can enhance health and physical performance in individuals that cannot exercise effectively.
External Links Taxonomy ID
39777
Genome Assembly ID
ASM154684v1
GOLD Organism ID
Go0006224
Disease Relevance
          Chronic kidney disease  [ICD-11: GB61]
             Description Veillonellaceae was associated with chronic kidney disease. [1]
          Periodontal disease  [ICD-11: DA0C]
             Description Periodontal disease was associated with Veillonella atypica. [2]
Host Genetic Factors (HGFs)
          hsa-miR-204-5p
             HGF ID HGF0207 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The microRNA-204 (miR-204) expression of Vascular is remotely regulated by the Veillonellaceae. [3]
          rs2069845
             HGF ID HGF1721 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The variant gene IL-6 of innate immunity rs2069845 is significantly associated with the abundance of gut micriobiota Veillonellaceae (p-value=0.0304). [4]
          rs17706060
             HGF ID HGF2198 HGF Info       Class Single Nucleotide Polymorphism (SNP)
             Description The rs17706060 SNP was significantly associated with the abundance of Veillonella atypica (p-value<1.00E-08). [5]
Host Immune Factors (HIFs)
          Tumor necrosis factor
             HIF ID HIFM0226 HIF Info       Class Cytokine (Cyt)
             Description Veillonellaceae abundance was associated with higher TNF-Alpha mRNA expression and serum insulin concentration. [6]
Environmental Factor(s)
             Disbiome ID
      479
             gutMDisorder ID
      gm0676
References
1 p-Cresyl Sulfate. Toxins (Basel). 2017 Jan 29;9(2):52. doi: 10.3390/toxins9020052.
2 Characterization of inhibitory effects of suspected periodontopathogens on osteogenesis in vitro. Infect Immun. 1995 Sep;63(9):3287-96.
3 Interactions between the MicroRNAs and Microbiota in Cancer Development: Roles and Therapeutic Opportunities. Allegra A, Musolino C, Tonacci A, Pioggia G, Gangemi S.. Cancers (Basel). 2020 Mar 27;12(4):805. doi: 10.3390/cancers12040805.
4 Variants in genes of innate immunity, appetite control and energy metabolism are associated with host cardiometabolic health and gut microbiota composition.Gut Microbes. 2020 May 3;11(3):556-568. doi: 10.1080/19490976.2019.1619440. Epub 2019 Jun 3.
5 Host genetic variation and its microbiome interactions within the Human Microbiome Project.Genome Med. 2018 Jan 29;10(1):6. doi: 10.1186/s13073-018-0515-8.
6 TRIM31 Deficiency Is Associated with Impaired Glucose Metabolism and Disrupted Gut Microbiota in Mice. Front Physiol. 2018 Feb 15;9:24. doi: 10.3389/fphys.2018.00024. eCollection 2018.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.