General Information of MIC (ID: MIC01817)
MIC Name Capnocytophaga sp. (CFB bacteria)
Body Site Oral Cavity
Lineage Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Flavobacteriia
Order: Flavobacteriales
Family: Flavobacteriaceae
Genus: Capnocytophaga
Species: Capnocytophaga sp.
Oxygen Sensitivity Anaerobe
Gram Negative
Description Capnocytophaga sp. is fusiform Gram-negative bacilli, and is part of the oral commensal flora.
External Links Taxonomy ID
44737
Genome Assembly ID
ASM1333370v1
GOLD Organism ID
Go0396213
Host Genetic Factors (HGFs)
          AMY1A
             HGF ID HGF2311 HGF Info       Class Copy Number Variation: Gene Duplication (CNV-GDu)
             Description Oral microbiome Capnocytophaga differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
          rs9836841
             HGF ID HGF1490 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs9836841 SNP was significantly associated with the abundance of Capnocytophaga (p-value=4.33E-06). [2]
          rs1252171
             HGF ID HGF1571 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs1252171 SNP was significantly associated with the abundance of Capnocytophaga sp (p-value<1.00E-08). [3]
          rs1219725
             HGF ID HGF1841 HGF Info       Class Single Nucleotide Polymorphism: Stop gained (SNP-SG)
             Description The rs1219725 SNP was significantly associated with the abundance of Capnocytophaga (p-value=8.27E-06). [2]
Environmental Factor(s)
             Disbiome ID
      97
             gutMDisorder ID
      gm0154
References
1 Human Salivary Amylase Gene Copy Number Impacts Oral and Gut Microbiomes.Cell Host Microbe. 2019 Apr 10;25(4):553-564.e7. doi: 10.1016/j.chom.2019.03.001.
2 Host genetic variation impacts microbiome composition across human body sites.Genome Biol. 2015 Sep 15;16(1):191. doi: 10.1186/s13059-015-0759-1.
3 Host genetic variation and its microbiome interactions within the Human Microbiome Project.Genome Med. 2018 Jan 29;10(1):6. doi: 10.1186/s13073-018-0515-8.

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