Details of Host Genetic Factor (HGF) Regulating Microbe Species (MIC)

General Information of HGF (ID: HGF2311)
HGF Name AMY1A
HGF Synonym(s) AMY1, amylase alpha 1A
Source Homo sapiens
HGF Classification Copy Number Variation: Gene Duplication (CNV-GDu)
Gene Location chr1
Gene Start Site 103655290 Gene End Site 103664554
Strand Forward (+)
External Links
Ensembl ID
ENSG00000237763
Microbe Species (MIC) Regulated by This HGF
         Actinobacillus equuli (gamma-proteobacteria) MIC01766
             Description Oral microbiome Actinobacillus differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Anaerostipes hadrus (firmicutes) MIC01441
             Description Gut microbiome Anaerostipes differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Bacteroides caccae (CFB bacteria) MIC00148
             Description The higher AMY1-CN has been associated with the abundance of Bacteroides caccae. [2]
         Bacteroides fragilis (CFB bacteria) MIC00158
             Description The higher AMY1-CN has been associated with the abundance of Bacteroides fragilis. [2]
         Bacteroides ovatus (CFB bacteria) MIC00167
             Description The higher AMY1-CN has been associated with the abundance of Bacteroides ovatus. [2]
         Bacteroides sp. (CFB bacteria) MIC00176
             Description Gut microbiome Bacteroides differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Bacteroides uniformis (CFB bacteria) MIC00184
             Description An higher AMY1-CN has been associated with the abundance of Bacteroides uniformis. [2]
         Barnesiellaceae (CFB bacteria) MIC00193
             Description Gut microbiome Barnesiellaceae differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Blautia producta (firmicutes) MIC00981
             Description Gut microbiome Blautia differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Campylobacter coli (epsilon-proteobacteria) MIC00301
             Description Oral microbiome Campylobacter differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Capnocytophaga sp. (CFB bacteria) MIC01817
             Description Oral microbiome Capnocytophaga differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Clostridia (firmicutes) MIC01851
             Description Oral microbiome Clostridia differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Collinsella stercoris (actinobacteria) MIC00435
             Description Gut microbiome Coriobacteriaceae differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Enterobacter sp. (enterobacteria) MIC00535
             Description The higher AMY1-CN has been significantly associated with the abundance of Enterobacteriaceae (p-value<0.05). [3]
         Erysipelothrix rhusiopathiae (firmicutes) MIC00559
             Description Gut microbiome Erysipelotrichaceae differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Faecalibacterium prausnitzii (firmicutes) MIC00590
             Description Gut microbiome Faecalibacterium prausnitzii differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Glaesserella parasuis (gamma-proteobacteria) MIC00654
             Description Oral microbiome Haemophilus differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Kingella sp. (beta-proteobacteria) MIC01896
             Description Oral microbiome Kingella differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Lachnospiraceae (firmicutes) MIC00695
             Description Gut microbiome Lachnospiraceae differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Leptotrichia goodfellowii (fusobacteria) MIC00762
             Description Oral microbiome Leptotrichia differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Mycoplasma pneumoniae (mycoplasmas) MIC00875
             Description The higher AMY1-CN has been associated with the abundance of Mycoplasma. [1]
         Neisseria sp. (beta-proteobacteria) MIC00900
             Description Oral microbiome Neisseriaceae differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Oscillospira sp. A (firmicutes) MIC00933
             Description Gut microbiome Oscillospira differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Parvimonas sp. (firmicutes) MIC01879
             Description The higher AMY1-CN has been associated with the abundance of Tissierellaceae parvimonas. [1]
         Phascolarctobacterium faecium (firmicutes) MIC00983
             Description Oral microbiome Veillonellaceae differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Porphyromonas sp. (CFB bacteria) MIC01003
             Description Oral microbiome Porphyromonas differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Prevotella copri (CFB bacteria) MIC01010
             Description The relative abundance of Prevotella copri, was twofold higher in adults with a high number of AMY1 copies (10) as compared to those with a low AMY1 copy number (4). [4]
         Prevotella sp. (CFB bacteria) MIC01024
             Description The relative abundance of Prevotella, was twofold higher in adults with a high number of AMY1 copies (10) as compared to those with a low AMY1 copy number (4). [4]
         Prevotella stercorea (CFB bacteria) MIC01431
             Description The relative abundance of Prevotella, was twofold higher in adults with a high number of AMY1 copies (10) as compared to those with a low AMY1 copy number (4). [4]
         Ruminococcus sp. (firmicutes) MIC01140
             Description Gut microbiome Ruminococcus differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Slackia exigua (actinobacteria) MIC01189
             Description Gut microbiome Coriobacteriaceae differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Streptococcus sp. (firmicutes) MIC01276
             Description Oral microbiome Streptococcus differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Sutterella parvirubra (beta-proteobacteria) MIC01291
             Description Gut microbiome Sutterella differs between high AMY1-CN and low AMY1-CN groups at the OTU Level (p-value<0.05). [1]
         Treponema pallidum (spirochaetes) MIC01325
             Description Oral microbiome Treponema differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
         Weeksella (CFB bacteria) MIC01952
             Description Oral microbiome Weeksellaceae differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
References
1 Human Salivary Amylase Gene Copy Number Impacts Oral and Gut Microbiomes.Cell Host Microbe. 2019 Apr 10;25(4):553-564.e7. doi: 10.1016/j.chom.2019.03.001.
2 Pretreatment Prevotella-to-Bacteroides ratio and salivary amylase gene copy number as prognostic markers for dietary weight loss.Am J Clin Nutr. 2020 May 1;111(5):1079-1086. doi: 10.1093/ajcn/nqaa007.
3 Human amylase gene copy number variation as a determinant of metabolic state.Expert Rev Endocrinol Metab. 2018 Jul;13(4):193-205. doi: 10.1080/17446651.2018.1499466.
4 Low Salivary Amylase Gene (AMY1) Copy Number Is Associated with Obesity and Gut Prevotella Abundance in Mexican Children and Adults.Nutrients. 2018 Nov 1;10(11):1607. doi: 10.3390/nu10111607.

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