| General Information of MIC (ID: MIC01431) |
| MIC Name |
Prevotella stercorea (CFB bacteria)
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| Body Site |
Gut
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| Lineage |
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Prevotellaceae
Genus: Prevotella
Species: Prevotella stercorea
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| Oxygen Sensitivity |
Anaerobe
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| Microbial Metabolism |
Saccharolytic, Fermentative
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| Gram |
Negative
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| Genome Size (bp) |
3092669
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| Description |
Prevotella stercorea is a species of the Prevotella. Prevotella species are Gram-negative rods most commonly associated with human oral colonization.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Host Genetic Factors (HGFs) |
| AMY1A |
| HGF ID |
HGF2311 |
HGF Info
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Class |
Copy Number Variation: Gene Duplication (CNV-GDu) |
| Description |
The relative abundance of Prevotella, was twofold higher in adults with a high number of AMY1 copies (10) as compared to those with a low AMY1 copy number (4). |
[1] |
| rs2072493 |
| HGF ID |
HGF1277 |
HGF Info
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Class |
Single Nucleotide Polymorphism: Missense variant (SNP-MV) |
| Description |
The variant gene TLR5 of innate immunity rs2072493 is significantly associated with the abundance of gut micriobiota Prevotella stercorea (p-value=0.0001). |
[2] |
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| Host Immune Factors (HIFs) |
| T cells |
| HIF ID |
HIFC0002 |
HIF Info
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Class |
T cells (TCs) |
| Description |
Prevotella abundance was specifically associated with the elevated numbers of activated Tc cells. |
[3] |
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| Environmental Factor(s) |
| Disbiome ID |
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| gutMDisorder ID |
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| References |
| 1 |
Low Salivary Amylase Gene (AMY1) Copy Number Is Associated with Obesity and Gut Prevotella Abundance in Mexican Children and Adults.Nutrients. 2018 Nov 1;10(11):1607. doi: 10.3390/nu10111607.
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| 2 |
Variants in genes of innate immunity, appetite control and energy metabolism are associated with host cardiometabolic health and gut microbiota composition.Gut Microbes. 2020 May 3;11(3):556-568. doi: 10.1080/19490976.2019.1619440. Epub 2019 Jun 3.
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| 3 |
The immune response to Prevotella bacteria in chronic inflammatory disease. Immunology. 2017 Aug;151(4):363-374. doi: 10.1111/imm.12760. Epub 2017 Jun 20.
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