General Information of MIC (ID: MIC01896)
MIC Name Kingella sp. (beta-proteobacteria)
Body Site Mucosa
Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Neisseriales
Family: Neisseriaceae
Genus: Kingella
Species: Kingella sp.
Oxygen Sensitivity Facultative anaerobe
Microbial Metabolism Saccharolytic; Fermentative
Gram Negative
Host Relationship Commensal
Description Kingella are Gram-negative organisms that colonize the human respiratory tract. They cause skeletal infections, endocarditis, and bacteremia and, rarely, pneumonia, epiglottitis, meningitis, abscesses, and ocular infections.
External Links Taxonomy ID
2020713
Host Genetic Factors (HGFs)
          AMY1A
             HGF ID HGF2311 HGF Info       Class Copy Number Variation: Gene Duplication (CNV-GDu)
             Description Oral microbiome Kingella differs between high AMY1-CN and low AMY1-CN groups at the OTU level (p-value<0.05). [1]
          rs890152
             HGF ID HGF1603 HGF Info       Class Single Nucleotide Polymorphism: Intron variant (SNP-IV)
             Description The rs890152 SNP was significantly associated with the abundance of unclassified Kingella (p-value<1.00E-08). [2]
          rs17630059
             HGF ID HGF2108 HGF Info       Class Single Nucleotide Polymorphism (SNP)
             Description The rs17630059 SNP was significantly associated with the abundance of unclassified Kingella (p-value<1.00E-08). [2]
          rs10156374
             HGF ID HGF1973 HGF Info       Class Single Nucleotide Polymorphism (SNP)
             Description The rs10156374 SNP was significantly associated with the abundance of unclassified Kingella (p-value<1.00E-08). [2]
Environmental Factor(s)
             Disbiome ID
      245
References
1 Human Salivary Amylase Gene Copy Number Impacts Oral and Gut Microbiomes.Cell Host Microbe. 2019 Apr 10;25(4):553-564.e7. doi: 10.1016/j.chom.2019.03.001.
2 Host genetic variation and its microbiome interactions within the Human Microbiome Project.Genome Med. 2018 Jan 29;10(1):6. doi: 10.1186/s13073-018-0515-8.

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