| General Information of MIC (ID: MIC01825) |
| MIC Name |
Dehalobacterium (firmicutes)
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| Body Site |
Gut
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| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Clostridiales
Family: Peptococcaceae
Genus: Dehalobacterium
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| Oxygen Sensitivity |
Obligate anaerobe
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| Microbial Metabolism |
Saccharolytic; Fermentative
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| Gram |
Positive
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| Description |
Dehalobacterium is a strictly anaerobic bacterium.
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| External Links |
Taxonomy ID |
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| GOLD Organism ID |
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| Host Genetic Factors (HGFs) |
| AVP |
| HGF ID |
HGF2328 |
HGF Info
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Class |
Copy Number Variation: Gene Deletion (CNV-GDe) |
| Description |
The deletion of AVP could significantly increase relative abundances of Dehalobacterium spp. (p-value<0.05). |
[1] |
| SLC15A1 |
| HGF ID |
HGF2354 |
HGF Info
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Class |
Copy Number Variation: Gene Deletion (CNV-GDe) |
| Description |
The deletion of PepT1 could increase the abundance of Dehalobacterium. |
[2] |
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| Host Immune Factors (HIFs) |
| Immunoglobulin A |
| HIF ID |
HIFM0272 |
HIF Info
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Class |
Immunoglobulin (Ig) |
| Description |
Dehalobacterium is significantly enriched in the IgA (Low or no IgA binding) consortia. |
[3] |
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| Environmental Factor(s) |
| Disbiome ID |
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| gutMDisorder ID |
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| References |
| 1 |
Vasopressin deletion is associated with sex-specific shifts in the gut microbiome.Gut Microbes. 2018 Jan 2;9(1):13-25. doi: 10.1080/19490976.2017.1356557. Epub 2017 Aug 11.
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| 2 |
Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations.NPJ Biofilms Microbiomes. 2020 Jul 21;6(1):27. doi: 10.1038/s41522-020-0137-y.
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| 3 |
IgA Function in Relation to the Intestinal Microbiota.Annu Rev Immunol. 2018 Apr 26;36:359-381. doi: 10.1146/annurev-immunol-042617-053238. Epub 2018 Jan 26.
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