General Information of MIC (ID: MIC01850)
MIC Name	Allobaculum (firmicutes)
Body Site	Gut
Lineage	Kingdom: Bacteria Phylum: Firmicutes Class: Erysipelotrichia Order: Erysipelotrichales Family: Erysipelotrichaceae Genus: Allobaculum
Oxygen Sensitivity	Aerobe
Microbial Metabolism	Respiratory
Gram	Positive
Description	Allobaculum is a Gram-positive, non-spore-forming bacterial, strictly anaerobic and non-motile genus from the family of Erysipelotrichidae, with one known species, Allobaculum stercoricanis.
External Links	Taxonomy ID	174708
	GOLD Organism ID	Go0542071

Host Genetic Factors (HGFs)
ARNTL
HGF ID	HGF2325	HGF Info	Class	Copy Number Variation: Gene Deletion (CNV-GDe)
Description	The deletion of BMAL1 could decrease relative abundances of Allobaculum (p-value<0.0001).				[1]
SLC15A1
HGF ID	HGF2354	HGF Info	Class	Copy Number Variation: Gene Deletion (CNV-GDe)
Description	The deletion of PepT1 could decrease the abundance of Allobaculum.				[2]

Host Immune Factors (HIFs)
Immunoglobulin A
HIF ID	HIFM0272	HIF Info	Class	Immunoglobulin (Ig)
Description	Allobaculum spp. were selectively IgA+ (High IgA binding) coated in patients with inflammatory bowel disease (Crohn disease and ulcerative colitis).				[3]

Environmental Factor(s)
Disbiome ID			1028
gutMDisorder ID			gm0689

References
1	Rhythmicity of the intestinal microbiota is regulated by gender and the host circadian clock.Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10479-84. doi: 10.1073/pnas.1501305112. Epub 2015 Aug 3.
2	Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations.NPJ Biofilms Microbiomes. 2020 Jul 21;6(1):27. doi: 10.1038/s41522-020-0137-y.
3	IgA Function in Relation to the Intestinal Microbiota.Annu Rev Immunol. 2018 Apr 26;36:359-381. doi: 10.1146/annurev-immunol-042617-053238. Epub 2018 Jan 26.

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