| General Information of MIC (ID: MIC01938) |
| MIC Name |
Lactobacillus murinus (firmicutes)
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| Body Site |
Gut
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| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactobacillus
Species: Lactobacillus murinus
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| Oxygen Sensitivity |
Anaerobe
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| Microbial Metabolism |
Fermentative
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| Gram |
Negative
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| Description |
Lactobacillus murinus is a new species isolated from rat and mouse digestivetracts. It can act as a probiotic to reduce the likelihood of hypertension.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Host Genetic Factors (HGFs) |
| FTO |
| HGF ID |
HGF2329 |
HGF Info
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Class |
Copy Number Variation: Gene Deletion (CNV-GDe) |
| Description |
The deletion of FTO could increase relative abundances of Lactobacillus murinus. |
[1] |
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| Host Immune Factors (HIFs) |
| CD103+Helios CD4+CD25+FOXP3+ regulatory T cells |
| HIF ID |
HIFC0186 |
HIF Info
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Class |
T cells (TCs) |
| Description |
Lactobacillus murinus is related to the expansion of colonic CD103+HeliosCD4+CD25+FOXP3+ Treg cell population. |
[2] |
| FOXP3+CD4+ regulatory T cells |
| HIF ID |
HIFC0199 |
HIF Info
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Class |
T cells (TCs) |
| Description |
Lactobacillus murinus is related to the increase of FOXP3+CD4+ Treg cells in the colon. |
[2] |
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| Environmental Factor(s) |
| Disbiome ID |
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| gutMDisorder ID |
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| References |
| 1 |
Fto Deficiency Reduces Anxiety- and Depression-Like Behaviors in Mice via Alterations in Gut Microbiota.Theranostics. 2019 Jan 24;9(3):721-733. doi: 10.7150/thno.31562. eCollection 2019.
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| 2 |
Development and maintenance of intestinal regulatory T cells.Nat Rev Immunol. 2016 May;16(5):295-309. doi: 10.1038/nri.2016.36. Epub 2016 Apr 18.
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