| General Information of HGF (ID: HGF0543) |
| HGF Name |
hsa-miR-375-5p
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| HGF Synonym(s) |
microRNA 375-5p, MIRN375-5p, MIR375-5p
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| Source |
Homo sapiens
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| HGF Classification |
Non-coding RNA: Micro (ncRNA-miRNA)
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| Gene Location |
chr2
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| Gene Start Site |
219001682
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Gene End Site |
219001704
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| Strand |
Reverse (-)
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| Sequence |
Click here to download the HGF sequence in FASTA format
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| External Links |
| miRBase ID |
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| Microbe Species (MIC) Regulated by This HGF |
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Helicobacter pylori (epsilon-proteobacteria)
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MIC00669
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| Description |
The miR-375 inhibits Helicobacter pylori-induced gastric carcinogenesis by blocking JAK2-STAT3 signaling. |
[1] |
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Porphyromonas gingivalis (CFB bacteria)
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MIC01000
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| Description |
The hsa-miR-375-5p was 2-fold up-regulation by Porphyromonas gingivalis in human gingival fibroblasts. |
[2] |
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| References |
| 1 |
Mechanisms of Inflammasome Signaling, microRNA Induction and Resolution of Inflammation by Helicobacter pylori. Curr Top Microbiol Immunol. 2019;421:267-302. doi: 10.1007/978-3-030-15138-6_11.
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| 2 |
MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts. J Inflamm (Lond). 2013 May 16;10(1):20. doi: 10.1186/1476-9255-10-20.
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