General Information of HGF (ID: HGF2330)
HGF Name	TLR5
HGF Synonym(s)	SLE1, TIL3, SLEB1, MELIOS, toll like receptor 5
Source	Homo sapiens
HGF Classification	Copy Number Variation: Gene Deletion (CNV-GDe)
Gene Location	chr1
Gene Start Site	223109404	Gene End Site		223143248
Strand	Reverse (-)
External Links
	Ensembl ID	ENSG00000187554

Microbe Species (MIC) Regulated by This HGF
Bacteroidetes (CFB bacteria)			MIC00141
Description	The deletion of TLR5 could significantly decrease relative abundances of Bacteroidetes (p-value<0.05).				[1]
Clostridiaceae (firmicutes)			MIC00376
Description	The deletion of TLR5 could significantly decrease relative abundances of Clostridiaceae (p-value<0.05).				[1]
Lachnospiraceae (firmicutes)			MIC00695
Description	The deletion of TLR5 influences the abundance of Lachnospiraceae.				[2]
Rikenella microfusus (CFB bacteria)			MIC01112
Description	The TLR5 was significantly associated with the decreased abundance of Rikenellaceae (p-value<0.05).				[1]
Sporobacter (firmicutes)			MIC01205
Description	The deletion of TLR5 could significantly decrease relative abundances of Sporobacter (p-value<0.05).				[1]

References
1	Deletion of the Toll-Like Receptor 5 Gene Per Se Does Not Determine the Gut Microbiome Profile That Induces Metabolic Syndrome: Environment Trumps Genotype.PLoS One. 2016 Mar 7;11(3):e0150943. doi: 10.1371/journal.pone.0150943. eCollection 2016.
2	Current understanding of the gut microbiota shaping mechanisms.J Biomed Sci. 2019 Aug 21;26(1):59. doi: 10.1186/s12929-019-0554-5.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.