| General Information of HGF (ID: HGF2337) |
| HGF Name |
MYD88
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| HGF Synonym(s) |
IMD68, MYD88D, MYD88 innate immune signal transduction adaptor
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| Source |
Homo sapiens
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| HGF Classification |
Copy Number Variation: Gene Deletion (CNV-GDe)
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| Gene Location |
chr3
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| Gene Start Site |
38138478
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Gene End Site |
38143022
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| Strand |
Forward (+)
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| External Links |
| Ensembl ID |
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| Microbe Species (MIC) Regulated by This HGF |
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Escherichia coli (enterobacteria)
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MIC00516
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| Description |
The magnitude of epithelial invasion by Escherichia coli was significantly increased when MyD88 was deleted. |
[1] |
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Klebsiella pneumoniae (enterobacteria)
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MIC01405
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| Description |
The deletion of MYD88 increased the abundance of Klebsiella pneumoniae. |
[1] |
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Salmonella enterica subsp. enterica (enterobacteria)
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MIC01154
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| Description |
The deletion of MYD88 showed the increased invasion of Salmonella typhimurium. |
[1] |
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| References |
| 1 |
Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides.Version 2. Mucosal Immunol. 2012 Sep;5(5):501-12. doi: 10.1038/mi.2012.23. Epub 2012 Apr 11.
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