Details of Host Genetic Factor (HGF) Regulating Microbe Species (MIC)
| General Information of HGF (ID: HGF2356) | |||||
|---|---|---|---|---|---|
| HGF Name | NLRP6 | ||||
| HGF Synonym(s) | AVR, NAVR, PAN3, NALP6, PYPAF5, CLR11.4, NAVR/AVR, NLR family pyrin domain containing 6 | ||||
| Source | Homo sapiens | ||||
| HGF Classification | Copy Number Variation: Gene Deletion (CNV-GDe) | ||||
| Gene Location | chr11 | ||||
| Gene Start Site | 278365 | Gene End Site | 285359 | ||
| Strand | Forward (+) | ||||
| External Links | |||||
| Ensembl ID | |||||
| Microbe Species (MIC) Regulated by This HGF | |||||
|---|---|---|---|---|---|
| Bacteroides sp. (CFB bacteria) | MIC00176 | ||||
| Description | The deletion of Nlrp6 could decrease the abundance of Bacteroidaceae. | [1] | |||
| Porphyromonas sp. (CFB bacteria) | MIC01003 | ||||
| Description | The deletion of Nlrp6 could increase the abundance of Porphyromonadaceae. | [1] | |||
| References | |||||
| 1 | Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition.Immunity. 2017 Aug 15;47(2):339-348.e4. doi: 10.1016/j.immuni.2017.07.011. Epub 2017 Aug 8. | ||||
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